i have used the trimix up to 60 days after thawing. What kind of sexual satisfaction would be possible? After 3 months the first two fears are largely allayed. Bi-mix lasts even longer. 3. Alprostadil lost 8% potency in five days at room temperature. For a better experience, please enable JavaScript in your browser before proceeding. I very much like my orgasms and having a hard time with the no ejaculation thing. 1 . The short outdate is gift from the FDA (another stellar government agency). I had three fears: His Father had it as well around the same age as him, so I am the youngest in the family to get it. My preparation has these concentrations: PGE1 (8.3 mcg/ml); Phentolamine (0.8 mg/ml); Papaverine (22.5 mg/ml).Is that similar to what others are using?Thank. It may not display this or other websites correctly. The one i am working on i keep in the fridge . We are a very sexually active couple. Since then the erections have not been 100%, 9/6/18: Diagnosed with prostate cancer after biopsy. Are you sure you want to block this member? Any advice. You can tell no difference between the first shot and the last. Frozen at -20 deg C and -70 deg C, less than 5% loss of any of the drug componnets occurred in 6 months. 9/26/18: Over the past few weeks, it has been recommended to me by 3 dif, Hi Due to my traveling I cant take the Injections on the road with me. Inspire is dedicated to helping you connect with others and learn as you share stories. My father had prostate cancer 4 years ago at the age of 64. I keep it refrigerated, used it successfully up to 18 months. I am four months post robotic RP and am about to start Trimix injections. this past January/18 for depression and regret at having had a prostatectomy and now no response, Been a month since leaving hospital and the fact that I had no nerve sparing the reality of ED is now hitting home. my tw, I was advised today by my urologist that my ED is caused by tissue or nerve damage from my treatment which was 3 months of ADT (Firmagon), External Beam radiation plus brachytherapy completed July 2015. My urologist/surgeon prescribed Tri-mix Super Mayo at 3 months after RRP. I use Bi-mix -- I keep it in the freezer and just thaw it out long enough to draw a few syringes which I then keep in the refrigerator for use. I found a bottle way back in the Refrigerator that is 3 years old (per mix).. By any chance would that bottle still be at any use or good? 3. Initially, I experienced a 9 out of 10 erection(4hr. Under refrigeration, it lost 6% potency after one month and 11% after two months. A brief history: When I spoke with the pharmacy, they said the formula had not changed, just the required outdate. All Rights Reserved. Gleason score 6 3+3 with a psa of 4.5 . Again, I don't recommend room temperature for more than two days. A. thanks in advance to all that reply.. If there is a problem with long term room temperature storage, it is one of bacteriological contamination. I prefill 20 syringes at a time. Room temperature exposure should be limited, and . Dealing with this has been a bigger adventure than I would like. Also by prefilling the syringes it'd less intrusive on the moment. Because of my husband's young age and his strong family history every doctor we have seen has recommended RP. I had 43 IMRT treatments that ended a year ago. Have my follow-up with my oncologist in a week or so. Surgeon said he spared the nerves but I'm wondering if that was really the case. I intend to keep using the vial as long as it works. However, results are not optimum and resulting erecting is painful to the point that intercourses is not enjoyable. Still trying to get a second opinion. Been using a pump for 3-4 months. 2. After reading on this site about pumps, got one and the results are similar. Does anybody know what the real out-date is? Stopped HCG, better libido and daily morning wood. I would also appreciate any female perspectives to this matter as well.My procedure was almost 3 years ago, and it was recommended that I have followup radiation. Gleason score of 6. I have kept trimix at room temperature for a week with no apparent loss of effectiveness. I had 5 of 12 cores positive. One has recommended the penile pump .. Refrigerated, Trimix loses strength at about 1% per week. i am still dripping enough to have to wear a light pad and feel gross. He adjusted it to 5 and it was almost as painful and then he went down to 4, missed the site and freaked us out (nothing happened of course) and then we had success a couple times. Alprostadil can be frozen for six months with 95% effectiveness. So heres something Id like some feedback on. Would all the cancer be removed? 2004 May-Jun;8(3):231-5. He is scheduled for surgery on Dec. 2nd. My oncologist says there is nothing to do at this point but keep checking every 4 months or so. i was thinking of stocking up. However, that information will still be included in details such as numbers of replies. When frozen, Trimix will last forever. So I am scared. I have been on the pecker power shots for over 25 years. Even if previously you never used to 'pleasure yourself' it is important that you should start now! Now I'm getting two different recommendations from two different Urologists.. Today we are beginning a partnership with The Mighty, a publisher of stories by and about people facing medical challenges. I wo, Dear members, Testosterone Replacement, Low T, HCG, & Beyond, Penis Injections for Hard Erections: TRIMIX, Hormonal Approach for Postmenopausal Vulvovaginal Atrophy, Done with TRT and recovered within two weeks. Stage t1c. The others 15-30 percent. I guess I'll try .2 cc next week. The Case Against Coronary Artery Calcium Scoring for Cardiovascular Disease Risk Assessment. I am a 46 year old male. Going to give nebido another shot! All lower left. My husband has been on Sildenafil 20 mg for almost a year since his Robotic prostatectomy. I then put those in a sun glass case along with my injector thingy. Daily Cialis didn't work. Told these are undectable? His brother is 14 years older and has stage 4 PC. I have visited a. Prescribed Caverject Impulse alprostadil 10 micrograms injection. Since my RRP in March, I've had no luck at all when it comes to recovering sexual function with regard to achieving erections. 2 of the votes were 40-60%. Papaverine and phentolamine , (two of the 3 ingredients in Trimix), can be kept at room temperature and won't degrade that much. Nobody knows my secret if I don't want them too. I am 16 weeks post robotic surgery for prostate removal, aged 64, happily married to my wife for 39 years. Gleason score of 6. Previously any male had 7 or 8 spontaneous, My husband is 52 years old and was diagnosed with stage one PC in June. Leaning toward prostatectomy. Need help understanding labs. Dr. i take viagra often with no effect. How long is trimix good for if kept refrigerated? Stress, Sleep, and Testosterone with Dr. Abe Morgentaler, BPC-157 to guard against Cipro induced tendon damage, Higher libido & more frequent erections from Ibuprofen & caffeine. usually its at the end of day or when tired etc. I know its largely unknown how or if and how much of any ED or incontinence one is likely to have based on your surgeon, anatomy, and how well you recover. I knew t, i am almost four months post robotic surgery. Alprostadil lost 6% effectiveness under refrigeration after 30 days. Alprostadil lost 44% effectiveness at room temperature after 30 days. At 34 weeks, the medication lost 25% and a 30% loss is seen after one full year at 41F. The doctor said at last visit when we ask how long should he take can stop whenever you feel you are ok. Well how do you know when you have taken enough, things could still improve, but guess that is typical advice from some docs. Viagra didn't work. To be honest, I cannot imagine interc, Anyone ever experience a contraindication with any mixture used for injection therapy? Not just about the cancer but if the side effects. Kept cold(not frozen), I don't think it really goes bad. After 20 weeks at 70F, a 37% loss was reported.. Now after a prostatectomy sex will never be the same again. My father had radiation and is doing well. I'm about to start Trimix injections to solve a problem worsened by radiation treatments for prostate cancer. I have used refrigerated syringes of Trimix up to 6 months with good results. 1. Hi - I was wondering if anyone out there has any experience with using a pump for ED after treatment for prostate cancer. Would any incontinence be endurable? Thinking about using injections but wanted some input before proceeding. My testosterone has returned to 300 so in the low normal range. Testosterone (no ester) Suspension for Injection - Literature Review. The other is recommending going straight to injections.. i have had 4 biopsies during This time and psa has crept up to 8.6 . Been taking 2 tabs of Viagra daily. At 70F (room temperature), alprostadil losts 10% effectiveness after 6 weeks. ZERO - The End of Prostate Cancer Support Community. A beyond-use date of 6 months when stored frozen at -20 deg C and 1 month when stored refrigerated at 4 deg C is appropriate for batches of the injection that have passed sterility testing. I keep them in there unrefrigerated until I run out. At what Free T level do you feel optimal? Maybe they dont know since all individuals are different in their re, Hi - I just came back from my Urologist after taking my first shot of Trimix. Has any one had a similar experience and if so, what happened when you upped the does? erections and one terrified man!) Alprostadil lost 2% effectiveness under refrigeration after seven days. Incontinence has not really been. A couple of years ago I went overseas and stayed for 7 weeks in countries mostly without fridges in hotel rooms and therefore there was no refrigeration for most that time. Hope that helps ease your concerns Roger. Urologist wanted to do removal surgery but I wasnt willing, so active surveillance for over 6 years now with 5 positive cores ( started with 2 ) out of 12 . 12Mg of Cypionate causing so many side effects? Does anybody know if they can in fact be re-frozen? 2. Int J Pharm Compd. After RP: Does anyone NOT suffer from ED. You are using an out of date browser. Can lowering cholesterol cause low testosterone? It's not over just different. he was diagnosed at 55. The ZERO - The End of Prostate Cancer Support Community connects patients, families, friends and caregivers to enhance the quality of life for all those affected by prostate cancer. What is one unexpected way a cancer diagnosis has impacted your life? I freeze the vial that is not yet being used. Welcome to ExcelMale.com, the leading and best-moderated mens health forum focused on increasing health, potency and productivity in men. At 2 weeks, I have noticed trimix is less effective. 2. If the vial is stored in cotton wool soaked in isopropyl alcohol in a plastic zip bag, you shouldn't have a problem. All treatment and consults at Mt Sinai in NY. , Human Chorionic Gonadotropin (HCG) Pregnyl, Why you should not use testosterone cream, Interview with Dr. Rich Sagall of NeedyMeds.org. This community is sponsored by ZERO - The End of Prostate Cancer, an Inspire trusted partner. Today, I received the drugs and syringes from a compounding pharmacy. A long time! Together we are launching a campaign to shed light on this question: What is one unexpected way a cancer diagnosis has impacted your, I was diagnosed 2/5/16 at 54 years old . im 48 and was diagnosed 3plus4 7 gleason, no escape from the prostate. Its even a bit weird talking with my wife on some of these issues. Now Im a 3+4 . Here is what I do and works great. I have been using Trimix for four and a half years and have had a total of 800 injections. But what Im wondering is if PC recovery has changed how men experience orgasm. also, i have no erectile response. However, I've seen a few comments online saying that the one-month instruction is CYA by the pharmacies and the drugs actually last much longer. If you do not refrigerate Trimix, prostraglandin, the third ingredient will slowly degrade. Left at room temperature (22C), Trimix loses strength at 1% per day. Now the urologist says I should do the seed implant. I have a question. I have been using trimix for about 4 years now.. Anyone use MUSE Urethral Suppositories in their rehab program? I have been using the same vial for more than two years (I don't use a lot, or need it every time). Cialis had no affect what so ever. If there is a problem with long term room temperature storage, it is one of bacteriological contamination. That was a couple months ago. There's hang on hunny while I fill my syringes and shoot up lol. Thankful I discovered this site to check out discussions that I would never have with my friends who have not had PC. It could take me sometimes 2-3 weeks until it's time to refill. My urologist/surgeon prescribed Cialis 5mg daily beginning 2 weeks prior to surgery. This was highly effective in producing an erection but i, Hi everyoneI need opinions.. Some comments recommend storing the drugs in a freezer, but the instructions say not to freeze them once they've been opened. Expert opinion suggests that ED sufferers need to get at least three erections a week. Not enough for penetration. I'm disappointed as it only resulted in about a 60% erection. No incontenience but struggling with erections. Was told that maybe wi, 4 months after RP, working to improve ED problems. He said he would start off with a low dose of .15 cc . I was aghast to read instructions saying that the drugs are good for only a month! For that I am happy and, Like many men who have had treatment for Prostate Cancer, I have had ED as a side effect. The effectiveness will be reduced approximately 10% per day so adjust your dose accordingly. I had to increase my dose, but I used it for 9 months! Alprostadil lost 12.5% effectiveness at room temperature after seven days. Left at room temperature (22C), Trimix loses strength at 1% per day. There are a lot of posts on the ED issues and the quality of an erection. My dad had very aggressive PC that spread to lymph-nodes. Being a relatively young 56 in PC terms I'm concerned about the impact this will have on my life. Stored in a syringe, alprostadil lost 10% effectiveness at 41F (refrigeration) after 24 weeks. with 10 units of Prostin(last October) but fast forward to this past June and having been prescribed Mirtazapine(Remeron)45mgs. No problem with administering and no pain. The good news is, after three PSA tests since the completion of my treatments, my PSA has remained below .1. My husband has NEVER had ED. I just sneak into the bathroom real quick, do my business and then get to business. Dr felt it before the biopsy. wow im surprised it would be that fast. I am recently married to, As I shared before the first time my husband did the injection at 10 in the office his erection was painful and lasted a little over 2 hours. If the vial is stored in cotton wool soaked in isopropyl alcohol in a plastic zip bag, you shouldn't . I'm in good health and fit. Sidenafil and Cialis don't provide a firm erection. He gets rock hard when the, Well it's been 6 months since my RPS and first PSA .10 and second .05. Find other members in this community to connect with. After 7 weeks I needed to increase the dose by about 70%, but it worked well at that dosage. 3. Basically, regardless of what pharmaceutical authorities tell you, the story is this : 1. Have questions about navigating your Inspire support community or need assistance from one of our Community Managers? As I'm a few weeks from my 80th birthday, there's no way I can use enough of it to make the cost per injection worthwhile. The good news is, my PSA has b, Hello. For a short, weekend trip, they are advised to draw up their syringe at about 1.25 times their normal dose and keep it at no more than room temperature (70F). So it would appear that those using Tri-mix could, when traveling, leave it. No previous history of sexual dysfunction. Well I would like to say I use 20 of them in a few days but I am no spring chicken lol. JavaScript is disabled. Refrigerated, Trimix loses strength at about 1% per week. The doctor gave me this first shot so I assume the inje, I am wondering if any men have experienced an almost total lack of spousal support and intimacy following your prostate cancer diagnosis and subsequent robotic nerve sparing radical prostatectomy. I was hoping to hear from others who can give me their tho, Most of us have a partner and sex was a thing that we always did together. bimix shots work great but i was hoping for a return of erectile function. He has a Gleason score of a six. I have a Gleason 3+4 = 7 and looking at the options. Frozen, alprostadil lost less than 5% after six months.. During that time I have frozen the stuff, refrigerated it and left it at room temperature and have studied the results. Currently on clomid. I bought one of those pump things and it was simply ineffective and painful. In reading online, I noticed that, while the three components seem to always be the same, the amounts/concentrations are not and can be variable. I keep it frozen all time ,I let melt draw a shot put Bach in freezer. Should I keep Tri-mix in the Refrigerator? I was recently diagnosed. 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