40% Detractors. In addition, the transaction is subject to the expiration or termination of the waiting period under the Hart-Scott-Rodino Antitrust Improvements Act of 1976 and other customary conditions. SOME OF THE STATEMENTS CONTAINED IN THIS ANNOUNCEMENT ARE FORWARD-LOOKING STATEMENTS, INCLUDING STATEMENTS REGARDING, AMONG OTHER THINGS, THE EXPECTED CONSUMMATION OF THE TRANSACTION, WHICH INVOLVES A NUMBER OF RISKS AND UNCERTAINTIES, INCLUDING THE SATISFACTION OF CLOSING CONDITIONS FOR THE TRANSACTION, INCLUDING REGULATORY APPROVAL, THE TENDER OF A MAJORITY OF THE OUTSTANDING SHARES OF COMMON STOCK OF SPARK THERAPEUTICS, THE POSSIBILITY THAT THE TRANSACTION WILL NOT BE COMPLETED, AND OTHER RISKS AND UNCERTAINTIES DISCUSSED IN SPARK THERAPEUTICS PUBLIC FILINGS WITH THE UNITED STATES SECURITIES AND EXCHANGE COMMISSION (THE SEC), INCLUDING THE RISK FACTORS SECTIONS OF SPARK THERAPEUTICS ANNUAL REPORT ON FORM 10-K FOR THE YEAR ENDED DECEMBER 31, 2017 AND SUBSEQUENT QUARTERLY REPORTS ON FORM 10-Q, AS WELL AS THE TENDER OFFER DOCUMENTS TO BE FILED BY ROCHE AND ITS ACQUISITION SUBSIDIARY AND THE SOLICITATION/RECOMMENDATION TO BE FILED BY SPARK THERAPEUTICS. This website uses cookies to improve your experience while you navigate through the website. About Spark Therapeutics . At Spark, we see the path to a world where no life is limited by genetic disease. Employees in the top 10 percent can make over $161,000 per year, while employees at the bottom 10 percent earn less than $55,000 per year. [1] It is a subsidiary of Hoffmann-La Roche . Roche has signed a definitive merger agreement to acquire all outstanding shares of US-based gene therapy company Spark Therapeutics for $114.50 per share, corresponding to a total of around $4.8bn on a fully diluted basis.. This corresponds to a total equity value of approximately $4.8 billion on a fully diluted basis, inclusive of approximately $500 million of projected net cash expected at close. The eye-popping $4.8 billion sticker price on Spark Therapeutics' acquisition deal with Roche announced on Monday is shaping up to be the largest exit ever within city limits for a venture-backed company, according to data from financial data provider PitchBook and the Philadelphia Alliance for Capital and Technologies (PACT). Federico began his scientific career studying the genetic basis of bleeding disorders. There, he spearheaded the development ofin vivogene therapies for inherited diseases. Prior to joining Bain in 2010, Michael was a partner at Monitor Group and head of the New York office, where he supported pharmaceutical treatment launches and growth strategies for 10 years. The stock has a consensus price target of $195.64. She is lean six sigma certified, has been a mentor through the Healthcare Businesswomens Association and is a past recipient of a WEST (Women in the Enterprise of Science and Technology) Giving Back Award. Necessary cookies are absolutely essential for the website to function properly. As the only biotechnology company that has successfully commercialized a gene therapy for a genetic disease in the U.S., we have built unmatched competencies in the discovery, development and delivery of genetic medicines. Necessary cookies are absolutely essential for the website to function properly. Spark Therapeutics chief executive officer Jeffrey D. Marrazzo said: "We had a strong second quarter, starting with the shipment of 12 vials of Luxturna (voretigene neparvovec-rzyl), as well as the work that went into the completion in early July of the transition to Pfizer and Phase 3 initiation of SPK-9001 for haemophilia B, now known as fidanacogene elaparvovec. Roche is the worlds largest biotech company, with truly differentiated medicines in oncology, immunology, infectious diseases, ophthalmology and diseases of the central nervous system. A world where no life is limited by genetic disease. Beyond his work at Spark, Paul plays an active role within community and cultural organizations, serving on the Boards of Directors for the Wharton Esherick Museum and the Jane Austen Society of North America. 40% Promoters. Spark Therapeutics, Inc. is a gene therapy company. philadelphia, feb. 25, 2019 (globe newswire) spark therapeutics (nasdaq: once), a fully integrated, commercial gene therapy company dedicated to challenging the inevitability of genetic disease, announced today that it has entered into a definitive merger agreement for roche to fully acquire spark therapeutics at a price of $114.50 per share in . Pre-clinical Immunology Lead Spark Therapeutics, Inc. Jennifer and her team are responsible for translating business priorities into talent, communication and engagement strategies that strengthen Sparks competitiveness and ability to fulfill its mission to challenge the inevitability of genetic disease. Spark Therapeutics will continue its operations in Philadelphia as an independent company within the Roche Group. With its worldwide reach and extensive resources, Roche will help us accelerate the development of more gene therapies for more patients for more diseases and further expedite our vision of a world where no life is limited by genetic disease., Spark Therapeutics proven expertise in the entire gene therapy value chain may offer important new opportunities for the treatment of serious diseases, said Severin Schwan, chief executive officer of Roche. These cookies do not store any personal information. CAUTIONARY STATEMENT REGARDING FORWARD-LOOKING STATEMENTS 9.9. Spark is a member of the Roche Group. Federico was involved in several first-in-human clinical studies of gene therapy based on the AAV vector platform while serving as the director of translational research the Center for Cellular and Molecular Therapeutics, at CHOP. Find out more about how we strive to turn genes into medicines for patients with inherited diseases, including inherited retinal diseases (IRDs), liver-directed diseases such as hemophilia, and neurodegenerative diseases. Cowen also acted as a financial advisor in this transaction to Spark Therapeutics. The combined strengths of pharmaceuticals and diagnostics under one roof have made Roche the leader in personalised healthcare a strategy that aims to fit the right treatment to each patient in the best way possible. Today, as a member of the Roche Group, Spark is focused on breaking barriers for people and families affected by genetic diseases, including blindness, hemophilia, lysosomal storage disorders and neurodegenerative disease, and currently has four programs in clinical trials. Abstract. 0 eNPS Score. At Spark Therapeutics, a fully integrated, commercial company committed to discovering, developing and delivering gene therapies, we challenge the inevitability of genetic diseases, including blindness, hemophilia, lysosomal storage disorders and neurodegenerative diseases. This website uses cookies and similar technologies to optimize and improve the experience on our site (, Return to Corporate Social Responsibility. Spark Therapeutics, Inc. PhD in Microbiology, INSA Toulouse, France About Responsible for establishing the Immunology Group at Spark Therapeutics and introducing multiple platforms to. . Federico also served as faculty at the Pierre and Marie Curie University in Paris, France, and Universitat Autonoma de Barcelona, Spain. Federico also served as faculty at the Pierre and Marie Curie University in Paris, France, and Universitat Autonoma de Barcelona, Spain. Head of Corporate Communications & Community Engagement Spark Therapeutics is developing potentially curative, one-time gene therapy products to transform the lives of patients and re-imagine the treatment of debilitating diseases. Any cookies that may not be particularly necessary for the website to function and is used specifically to collect user personal data via analytics, ads, other embedded contents are termed as non-necessary cookies. The national average salary for a Spark Therapeutics employee in the United States is $94,398 per year. Report Job. Apply to Bioanalytical Study Lead, Administrative Assistant, Laboratory Technician and more! Centerview Partners is acting as financial advisor to Spark Therapeutics and Goodwin Procter LLP is acting as legal counsel to Spark Therapeutics. 4.4/5 on G2 Crowd. In March 2020, after consultation with global investigators, advocacy leadership, and healthcare experts, and in an abundance of caution for the health and safety of people with Pompe disease, Spark Therapeutics decided to voluntarily suspend enrollment into . Under the terms of the merger agreement, Roche will promptly commence a tender offer to acquire all outstanding shares of Sparks common stock, and Spark will file a recommendation statement containing the unanimous recommendation of the Spark board that Spark shareholders tender their shares to Roche. Federico received his bachelors degree in biology and his Ph.D. in biochemistry and molecular biology from the University of Ferrara in Italy, and his M.B.A. from Drexel University. Greater understanding of the human genome and genetic abnormalities have allowed our scientists to tailor investigational therapies to patients suffering from very specific genetic diseases. Industry. You also have the option to opt-out of these cookies. Phone: 1-855-SPARKTX / +1 215-220-9300. His work continued to focus on the characterization of human immune responses to AAV vectors and on the development of strategies to overcome immune responses in gene transfer. Paul joined Spark in 2016, and most recently served as General Counsel. Spark Therapeutics Profile and History . At Spark, the vision is a world where no life is limited by a genetic disease. Roche to acquire Spark Therapeutics for $114.50 per share representing a total equity value of $4.8 billion Spark Therapeutics will continue its operations in Philadelphia as an independent company within the Roche Group Transaction expected to close in Q2, 2019. Paul Savidge serves as Chief Legal Officer at Spark Therapeutics, where he brings more than 25 years of experience in the biopharmaceutical industry. State-of-the-art, in-house expertise in vector manufacturing, Innovative scientific and regulatory strategies, Strong commitment to improve patient care, This website uses cookies and similar technologies to optimize and improve the experience on our site (. You also have the option to opt-out of these cookies. Her expertise is centered in business transformations and, organizational effectiveness, change management, HR effectiveness and creating employee-centric solutions. At Spark Therapeutics, a fully integrated, commercial company committed to discovering, developing and delivering gene therapies, we challenge the inevitability of genetic diseases, including blindness, hemophilia, lysosomal storage disorders and neurodegenerative diseases. About Spark Therapeutics . He also was responsible for the other functions, including commercial development, marketing, pricing and reimbursement, government affairs, program and alliance management, commercial operations, diagnostics, market access and patient services functions. Spark Therapeutics Inc: Dir & Bioassay Lead, Analytical Sciences & Quality Control: Spark Therapeutics Inc: Head, Immunology: Spark Therapeutics Inc: Research Assoc Immunomonitoring, Translational Immunology & Bioanalysis: Spark Therapeutics Inc: Sr Research Assoc, Assay Dev: Spark Therapeutics Inc: Sr Scientist: Spark Therapeutics Inc: Team . Out of these cookies, the cookies that are categorized as necessary are stored on your browser as they are essential for the working of basic functionalities of the website. These cookies will be stored in your browser only with your consent. Previous personnel management. Associated People Federico Mingozzi Glassdoor provides our best prediction for total pay in today's job market, along with other types of pay like cash bonuses, stock bonuses, profit sharing, sales commissions, and tips. . About Spark Therapeutics Find jobs. Spark Therapeutics, a unit of Roche Holdings AG (OTC: RHHBY), has announced data from its Phase 1/2 trial of SPK-8011 in hemophilia A. IF UNDERLYING ASSUMPTIONS PROVE INACCURATE OR UNKNOWN RISKS OR UNCERTAINTIES MATERIALIZE, ACTUAL RESULTS AND THE TIMING OF EVENTS MAY DIFFER MATERIALLY FROM THE RESULTS AND/OR TIMING DISCUSSED IN THE FORWARD-LOOKING STATEMENTS, AND YOU SHOULD NOT PLACE UNDUE RELIANCE ON THESE STATEMENTS. This ecosystem will ultimately benefit students through co-ops and career opportunities, benefit faculty through collaborative research and training, and benefit the surrounding community through the creation of a pipeline to employment. Paul is also a member of the Roche General Counsels Leadership Circle. In 2018, Roche invested CHF 11 billion in R&D and posted sales of CHF 56.8 billion. Roche is the majority shareholder in Chugai Pharmaceutical, Japan. Our initial focus is on treating orphan diseases. It is also responsible for the proof-of-concept studies design and execution for treatment of autoimmune diseases, choice of autoimmune indications and establishing the candidate . as a member of larger immunology team in the translational department, the preclinical immunology lead is responsible for strategic planning, execution, and reporting of pre-clinical immunology studies; initiates and directs immunological initiatives to support all spark therapeutic areas with the goal of increasing safety and efficacy of all The closing of the tender offer will be subject to a majority of Spark Therapeutics outstanding shares being tendered. Leadership truly cares about employee engagement and workplace satisfaction. But the needs of patients and families living with genetic diseases are immediate and vast, said Jeffrey D. Marrazzo, chief executive officer of Spark Therapeutics. Contents 1 History 2 Products and pipeline 2.1 Voretigene neparvovec 2.2 Fidanacogene elaparvovec 2.3 SPK-8011 2.4 SPK-7001 2.5 SPK-3006 2.6 SPK-1001 3 References 4 External links from the University of California, Berkeley. We are proud to partner with Spark Therapeutics in advancing life sciences research and innovation in University City, said John Fry, president, Drexel University. We have built a fully integrated company, combining our proprietary adeno-associated viral (AAV) gene therapy platform with excellence in R&D, manufacturing and commercial operations. THE OFFER TO PURCHASE, SOLICITATION/RECOMMENDATION STATEMENT AND RELATED MATERIALS WILL BE FILED WITH THE SEC, AND INVESTORS AND SECURITY HOLDERS MAY OBTAIN A FREE COPY OF THESE MATERIALS (WHEN AVAILABLE) AND OTHER DOCUMENTS FILED BY ROCHE AND SPARK THERAPEUTICS WITH THE SEC AT THE WEBSITE MAINTAINED BY THE SEC AT WWW.SEC.GOV. To further aid in attraction and retention, starting in 2022, we will offer expanded mental health resources and extend benefits to part-time employees. He oversees Sparks Legal and Compliance departments, which he has significantly contributed to building and developing during his nearly six-year tenure with the company. Construction of Sparks new gene therapy innovation center is anticipated to begin in the fourth quarter of 2022. The Company focuses on treating orphan diseases. Jennifer holds a B.S. Since the initial evidence that AAV vectors can elicit capsid T cell responses in humans, which can affect the duration . We don't follow footsteps. Our shared mission is to challenge the inevitability of genetic disease by discovering, developing, and delivering treatments in ways unimaginable - until now. WOBURN, Mass., May 26, 2022 (GLOBE NEWSWIRE) -- Replimune Group, Inc. (NASDAQ:REPL), a clinical stage biotechnology company pioneering the development of a novel class of tumor-directed oncolytic. THE SOLICITATION AND OFFER TO BUY SPARK THERAPEUTICS COMMON STOCK WILL ONLY BE MADE PURSUANT TO AN OFFER TO PURCHASE AND RELATED MATERIALS. In addition to Sparks physical expansion, the announcement marks the beginning of a long-term partnership with Drexel University and is part of Sparks larger commitment to sparking positive change in the Philadelphia community. Scientist (Current Employee) - Philadelphia, PA - June 11, 2021. Generally, has 6 years of relevant post-graduate experience in biotech or biopharma. Phone: 1-855-SPARKTX / +1 215-220-9300. Throughout his distinguished career, Federico has received several awards and has contributed to the field of gene therapy with more than 100 scientific publications, including seminal findings in the field of AAV gene therapy. communications@sparktx.com or 267-583-8267, Drexel University Federico began his scientific career studying the genetic basis of bleeding disorders. THIS ANNOUNCEMENT IS FOR INFORMATIONAL PURPOSES ONLY AND DOES NOT CONSTITUTE AN OFFER TO PURCHASE OR A SOLICITATION OF AN OFFER TO SELL SPARK THERAPEUTICS COMMON STOCK. Spark Therapeutics, Inc. is hiring for a Scientist Immunology in Philadelphia, PA . 109 Spark Therapeutics jobs available in Camden, NJ on Indeed.com. This approach holds great promise in developing effective treatments to a host of inherited diseases. Jennifer joined Spark in 2017 and previously served as the Head of HR, leading the team that recruited, hired and onboarded hundreds of team members to more than double the Companys size over four-year period. You also have the option to opt-out of these cookies. She served as Vice President of HR for Teva Pharmaceuticals, leading the HR function for its U.S. business, and at Shire Pharmaceuticals (now part of Takeda), as the Chief of Staff to the CHRO, in addition to a number of senior-level HR Business Partner roles. Paul holds a BSFS from Georgetown Universitys School of Foreign Service, an M.B.A. from the Kellogg School of Management at Northwestern University, and a JD from Washington and Lee University School of Law. Our mission at Spark Therapeutics is to challenge the inevitability of genetic disease by discovering, developing and delivering potential treatments in ways unimaginableuntil now. Dr. Federico Mingozzi is the chief scientific officer at Spark Therapeutics, bringing two decades of experience in gene therapy, immunology, as well as biochemistry and molecular biology in both industry and academic settings. Spark is a member of the Roche Group. Ron is a graduate of Drexel University. Terms of the Agreement These cookies will be stored in your browser only with your consent. We are glad to share with you an update on the status of the Pompe clinical development program at Spark Therapeutics. He is also a member of the Health Law Advisory Board of Drexel Universitys Thomas R. Kline School of Law. This category only includes cookies that ensures basic functionalities and security features of the website. You also have the option to opt-out of these cookies. About Roche Roche is the world's largest biotech company, with truly differentiated medicines in oncology, immunology, infectious diseases, ophthalmology and diseases of the . Friendly and collaborative colleagues and supportive management team. The merger agreement has been unanimously approved by the boards of both Spark and Roche. As Spark Therapeutics Chief Executive Officer, Ron Philip leads a team of talented individuals working together to develop new therapies for people living with genetic diseases. Roche . Welcome back Sign in to save Senior Scientist - Immunology at Spark Therapeutics, Inc.Senior Scientist - Immunology at Spark Therapeutics, Inc. As part of Sparks now projected 1 million-square-foot campus in Philadelphia, the anticipated 500,000-square-foot, multi-story building will bring hundreds of the greatest minds in gene therapy together under one roof to drive science forward, challenge the inevitability of genetic disease, and serve as a Roche global center of excellence for gene therapy manufacturing. in biochemistry from the University of Waterloo in Canada. On December 19, 2017, the FDA approved a novel gene therapy that treats diseases that affect vision. Find more details about the job and how to apply at Built In. Philadelphia, Pennsylvania, United States - Part of a team testing the immunogenicity of AAV-based gene . Federico was involved in several first-in-human clinical studies of gene therapy based on the AAV vector platform while serving as the director of translational research the Center for Cellular and Molecular Therapeutics, at CHOP. Dr. Gallia Levy is the Chief Medical Officer at Spark Therapeutics and leads strategic and operational teams throughout the product development lifecycle with responsibility for setting the global development strategy for current and pipeline programs. Before that, Michael was senior vice president at Sanofi Diagnostics Pasteur in Paris, France and a senior director at Boehringer Mannheim (now Roche) in Mannheim, Germany. THE TENDER OFFER FOR THE OUTSTANDING COMMON STOCK OF SPARK THERAPEUTICS HAS NOT BEEN COMMENCED. Roche is the world's largest biotech company, with truly differentiated medicines in oncology, immunology, infectious diseases, ophthalmology and diseases of the . Skip to main content. These cookies do not store any personal information. In particular, Sparks hemophilia A program could become a new therapeutic option for people living with this disease. He also led studies aimed at the characterization of human immune responses to AAV vectors and the development of strategies to modulate vector immunogenicity. Address Philadelphia, PA. 19104 USA. About Spark Therapeutics Spark Therapeutics is a fully integrated, commercial company committed to discovering, developing and delivering gene therapies . Select a reason for reporting this job. THESE STATEMENTS ARE GENERALLY IDENTIFIED BY WORDS OR PHRASES SUCH AS BELIEVE, ANTICIPATE, EXPECT, INTEND, PLAN, WILL, MAY, SHOULD, ESTIMATE, PREDICT, POTENTIAL, CONTINUE OR THE NEGATIVE OF SUCH TERMS OR OTHER SIMILAR EXPRESSIONS. Senior Vice President, Head of Development Sciences, Spark Therapeutics, a Roche subsidiary Bridgewater, New Jersey, United States . INVESTORS AND SECURITY HOLDERS ARE URGED TO READ THESE MATERIALS (INCLUDING AN OFFER TO PURCHASE, A RELATED LETTER OF TRANSMITTAL AND CERTAIN OTHER TENDER OFFER DOCUMENTS) CAREFULLY WHEN THEY BECOME AVAILABLE SINCE THEY WILL CONTAIN IMPORTANT INFORMATION, INCLUDING THE TERMS AND CONDITIONS OF THE OFFER.
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